How much the text and screen-reader output says.
Whether sonification is on.
Whether the braille field is open.
Whether high contrast colours are on (a saved setting).
Whether newly appended points of a live chart are announced.
Whether autoplay is moving the cursor.
The rotor mode the arrow keys move in: data for ordinary navigation,
else lower, higher, grid, point, intersection or filter:<unit>.
The modes a reader has in a chart: what the command palette's toggles and autoplay keys change.